IVF Step 4: Preparing your womb to receive the embryos

Your womb will need to be prepared before it can receive the fertilised eggs (embryos). Embryos are more likely to attach themselves to the sides of the womb (implant) and develop into a baby if the lining of the womb is thick and rich in blood vessels.

You will be given a drug that keeps the lining of your womb thick and gives your embryos the best possible chance of survival. This drug works in the same way as the hormone “progesterone.” Progesterone is released in your body naturally every month, just before you have your period. Its job is to keep the lining of your womb thick in case an egg is fertilised. When progesterone levels drop, you have a period.

The drug that is given is called Utrogestan. You will need to start taking this drug at the same time as you take the drug to mature your eggs (Pregnyl – see step 3).

Utrogestan is usually taken vaginally before you have your embryos put back in your womb. You will need to take the tablets at bedtime, as one of the side effects is drowsiness. You will need to continue taking Utrogestan after your embryos have been replaced.

You may be given another drug that works in the same way as Utrogestan, such as Crinone cream.

Taking Utrogestan helps keep the lining of your womb thick and gives your embryos the best possible chance of implanting and growing in your womb.

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